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赵蔚明
作者:  来源:  发布时间:2016-09-18 21:00:05  浏览次数:915

赵蔚明,女,1956年12月 出生,医学博士,教授,博士生导师。 现任中国微生物学会医学微免专业委员会委员山东省医学会微免分会名誉主委。医学微生物学(卫生部“十二五”规划教材) 编委。主要从事人乳头瘤病毒致宫颈癌的分子机制研究,衣原体感染与免疫研究。

在研项目:  

1. 宿主抗肺炎衣原体感染中NKT细胞对NK细胞调节作用的研究,2013.1-2016.12, 国家自然科学基金面上项目, 主持人

 

2.抑癌基因LKB1及其新靶标INPP4B在宫颈癌细胞中的功能与调控,2015.1-2018.12, 国家自然科学基金面上项目, 主持人  

 

代表性学术论文:

 

1. Li J, Dong X, Zhao L, Wang X, Wang Y, Yang X, Wang H*, Zhao W*Natural killer cells regulate Th1/Treg and Th17/Treg balance in chlamydial lung infection. J Cell Mol Med. 2016 Jul;20(7):1339-51.( * Correspondence Author )

2.Zhang W*Chen HChen YLiu JWang XYu XChen JJZhao W*. Cancerous inhibitor of protein phosphatase 2A contributes to human papillomavirus oncoprotein E7-induced cell proliferation via E2F1 Oncotarget 2015,6(7):5253-5262.( * Correspondence Author )

3. Zhang X, Chen H, Wang X, Zhao W*, Chen JJ*. Expression and transcriptional profiling of the LKB1 tumor suppressor in cervical cancer cells. Gynecol Oncol.  2014 Aug;134(2):372-8 .( * Correspondence Author )

4. Zheng L, Tang W, Wei F, Wang H, Liu J, Lu Y, Cheng Y, Bai X, Yu X*, Zhao W*. Radiation-inducible protein RbAp48 contributes to radiosensitivity of cervical cancer cells.  Gynecol Oncol. 2013 Sep;130(3):601-8. ( * Correspondence Author )

5. Peng Y, Zhao L, Shekhar S, Liu L, Wang H, Chen Q, Gao X, Yang X*, Zhao W*The glycolipid exoantigen derived from Chlamydia muridarum activates invariant natural killer T cells. Cell Mol Immunol. 2012 Jul;9(4):361-6.  ( * Correspondence Author )

6. Wang X, Qi M, Yu X, Yuan Y*, Zhao W*. Type-specific interaction between human papillomavirus type 58 E2 protein and E7 protein inhibits E7-mediated oncogenicity. J Gen Virol. 2012 Jul;93(Pt 7):1563-72. ( * Correspondence Author )

7.Wang H, Zhao L, Peng Y, Liu J, Qi M, Chen Q, Yang X, Zhao W*. Protective role of α-galactosylceramide-stimulated natural killer T cells in genital tract infection with Chlamydia muridarum. FEMS Immunol Med Microbiol. 2012 Jun;65(1):43-54. ( * Correspondence Author )

8. Zhao L, Gao X, Peng Y, Joyee AG, Bai H, Wang S, Yang J, Zhao W*, Yang X*. Differential modulating effect of natural killer (NK) T cells on interferon-γ production and cytotoxic function of NK cells and its relationship with NK subsets in Chlamydia muridarum infection. Immunology. 2011 Oct;134(2):172-84. ( * Correspondence Author )

9. Liu J, Wang X, Zhou G, Wang H, Xiang L, Cheng Y, Liu w, Wang Y, Jia J, Zhao W*.  Cancerous inhibitor of protein phosphatase 2A is overexpressed in cervical cancer and upregulated by human papillomavirus 16 E7 oncoprotein. Gynecol Oncol. 2011 Aug;122(2):430-6.  ( * Correspondence Author )

10. Jing Li, Xiao Wang, Juan Liu, Hong Wang, Xiao-Li Zhang, Wei Tang, Yun-Dong Sun, Xin Wang, Xiu-Ping Yu,Wei-Ming Zhao*. Replication and transcription of human papillomavirus type 58 genome in Saccharomyces cerevisiae. VIROL J. 2010, 7:368.  ( * Correspondence Author )

 
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